| Gene Information | |
|---|---|
| Gene Name | POFUT1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 388 |
| Protein Names | GDP-fucose protein O-fucosyltransferase 1 (EC 2.4.1.221) (Peptide-O-fucosyltransferase 1) (O-FucT-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 132 ( ENSG00000101346 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9H488 |
| Gene Card | POFUT1 |
| Uniprot ID | Q9H488 |
| Pfam | PF10250 |
| In ASD | no |
| Allosteric Prediction | no (-0.363320969) |
| Ortholog in Animals | Alpaca_ POFUT1 ( ortholog_one2one ) Dog_ POFUT1 ( ortholog_one2one ) GuineaPig_ POFUT1 ( ortholog_one2one ) Macaque_ POFUT1 ( ortholog_one2one ) Mouse_ Pofut1 ( ortholog_one2one ) Pig_ POFUT1 ( ortholog_one2one ) Rat_ Pofut1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:11524432}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5UX6 (X-ray 2.09A ) 5UXH (X-ray 2.41A ) |
| DBSNP | rs17268666 rs35259534 |
| Subcellular location [CC] | Endoplasmic reticulum {ECO:0000250|UniProtKB:Q6EV70}. |
| Mouse PG classification | LPG |
| click here to return to the previous page | |