| Gene Information | |
|---|---|
| Gene Name | POC1A |
| Organism | Homo sapiens (Human) |
| Gene Length | 407 |
| Protein Names | POC1 centriolar protein homolog A (Pix2) (Proteome of centriole protein 1A) (WD repeat-containing protein 51A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000164087 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q8NBT0 |
| Gene Card | POC1A |
| Uniprot ID | Q8NBT0 |
| Pfam | PF00400 |
| In ASD | no |
| Allosteric Prediction | no (-1.114822354) |
| Ortholog in Animals | Alpaca_ POC1A ( ortholog_one2one ) Dog_ POC1A ( ortholog_one2one ) GuineaPig_ POC1A ( ortholog_one2one ) Macaque_ POC1A ( ortholog_one2one ) Mouse_ Poc1a ( ortholog_one2one ) Pig_ POC1A ( ortholog_one2one ) Rat_ Poc1a ( ortholog_one2one ) Rabbit_ POC1A ( ortholog_one2one ) |
| Ohnologs | POC1B |
| Paralogs | DAW1, WDR43, WDR7, COP1, TBL2, POC1B, WDR88, PAFAH1B1, WDR17, NWD1, WDR62, PAK1IP1, DCAF4L1, WDR27, WDR5B, WDR5, NEDD1, MAPKBP1, AHI1, TEP1, SNRNP40, WDR75, WDR81, DCAF4L2, DCAF4, WDR38 |
| Tissue | testis |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002990(Rat);0.04(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35249554 rs397514488 rs35898691 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:14654843}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, spindle pole. Note=Component of both mother and daughter centrioles. |
| Mouse PG classification | NA |
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