| Gene Information | |
|---|---|
| Gene Name | CLIC6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 704 |
| Protein Names | Chloride intracellular channel protein 6 (Parchorin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000159212 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96NY7 |
| Gene Card | CLIC6 |
| Uniprot ID | Q96NY7 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.647496165) |
| Ortholog in Animals | Alpaca_ CLIC6 ( ortholog_one2one ) Dog_ CLIC6 ( ortholog_one2one ) Macaque_ CLIC6 ( ortholog_one2one ) Mouse_ Clic6 ( ortholog_one2one ) Pig_ CLIC6 ( ortholog_one2one ) Rat_ Clic6 ( ortholog_one2one ) |
| Ohnologs | CLIC2, CLIC5, CLIC4 |
| Paralogs | CLIC2, GSTZ1, GSTO2, GDAP1L1, CLIC3, GSTT4, CLIC4, GSTT2, GSTT2B, CLIC1, EEF1G, GDAP1, GSTO1, CLIC5 |
| Tissue | stomach |
| Tissue Specificity | Expressed in brain, placenta, pancreas and liver. {ECO:0000269|PubMed:12226712}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);0.001990(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3171439 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Note=Predominantly cytoplasmic. Upon chloride ion efflux from the cell, it is translocated to the plasma membrane (By similarity). {ECO:0000250}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |