| Gene Information | |
|---|---|
| Gene Name | PNPO |
| Organism | Homo sapiens (Human) |
| Gene Length | 261 |
| Protein Names | Pyridoxine-5'-phosphate oxidase (EC 1.4.3.5) (Pyridoxamine-phosphate oxidase) |
| Target Name | pyridoxine-5'-phosphate oxidase |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000108439 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9NVS9 |
| Gene Card | PNPO |
| Uniprot ID | Q9NVS9 |
| Pfam | PF10590; PF01243 |
| In ASD | yes |
| Allosteric Prediction | yes (0.190494457) |
| Ortholog in Animals | Alpaca_ PNPO ( ortholog_one2one ) Dog_ PNPO ( ortholog_one2one ) GuineaPig_ PNPO ( ortholog_one2one ) Macaque_ PNPO ( ortholog_one2one ) Mouse_ Pnpo ( ortholog_one2one ) Pig_ PNPO ( ortholog_one2one ) Rat_ Pnpo ( ortholog_one2one ) Rabbit_ PNPO ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. Expressed in liver, brain, lung, prostate and stomach (at protein level). {ECO:0000269|PubMed:15182361}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1NRG (X-ray 1.95A ) 3HY8 (X-ray 2.50A ) 6H00 (X-ray 1.66A ) |
| DBSNP | rs549477447 rs17679445 rs550423482 rs773450573 rs104894629 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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