| Gene Information | |
|---|---|
| Gene Name | ABCB8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 735 |
| Protein Names | Mitochondrial potassium channel ATP-binding subunit (ATP-binding cassette sub-family B member 8, mitochondrial) (ABCB8) (Mitochondrial ATP-binding cassette 1) (M-ABC1) (Mitochondrial sulfonylurea-receptor) (MITOSUR) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000197150 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q9NUT2 |
| Gene Card | ABCB8 |
| Uniprot ID | Q9NUT2 |
| Pfam | PF00664; PF00005 |
| In ASD | no |
| Allosteric Prediction | no (-0.045393338) |
| Ortholog in Animals | Alpaca_ ABCB8 ( ortholog_one2one ) Dog_ ABCB8 ( ortholog_one2one ) GuineaPig_ ABCB8 ( ortholog_one2one ) Macaque_ ABCB8 ( ortholog_one2one ) Mouse_ Abcb8 ( ortholog_one2one ) Pig_ ABCB8 ( ortholog_one2one ) Rat_ Abcb8 ( ortholog_one2one ) Rabbit_ ABCB8 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ABCB6, TAP1, ABCB11, ABCB4, ABCB9, TAP2, ABCB7, ABCB1, ABCB10, ABCB5 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5OCH (X-ray 3.40A ) 7EHL (EM - ) |
| DBSNP | rs4148844 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000269|PubMed:16259955, ECO:0000269|PubMed:31435016}; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}. |
| Mouse PG classification | NA |
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