| Gene Information | |
|---|---|
| Gene Name | PNP |
| Organism | Homo sapiens (Human) |
| Gene Length | 95 |
| Protein Names | Pancreatic prohormone (Pancreatic polypeptide) (PP) (Obinepitide) [Cleaved into: Pancreatic hormone (PH); Pancreatic icosapeptide (PI)] |
| Target Name | purine nucleoside phosphorylase |
| Target Type | Clinical trial target |
| Gene Age | 645 ( ENSG00000198805 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P01298 |
| Gene Card | PPY |
| Uniprot ID | P01298 |
| Pfam | PF00159 |
| In ASD | no |
| Allosteric Prediction | yes (0.571315092) |
| Ortholog in Animals | Alpaca_ PNP ( ortholog_one2one ) Dog_ PNP ( ortholog_one2one ) GuineaPig_ PNP ( ortholog_one2one ) Mouse_ Pnp ( ortholog_one2many ) Mouse_ Pnp2 ( ortholog_one2many ) Pig_ PNP ( ortholog_one2one ) Rat_ Pnp ( ortholog_one2one ) Rabbit_ PNP ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MTAP |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1TZ4 (NMR - ) 1TZ5 (NMR - ) 7X9C (EM 3.00A ) |
| DBSNP | rs7215698 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
| click here to return to the previous page | |