| Gene Information | |
|---|---|
| Gene Name | PNOC |
| Organism | Homo sapiens (Human) |
| Gene Length | 176 |
| Protein Names | Prepronociceptin [Cleaved into: Nocistatin; Nociceptin (Orphanin FQ) (PPNOC); Orphanin FQ2] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000168081 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q13519 |
| Gene Card | PNOC |
| Uniprot ID | Q13519 |
| Pfam | PF01160 |
| In ASD | no |
| Allosteric Prediction | yes (0.354872529) |
| Ortholog in Animals | Alpaca_ PNOC ( ortholog_one2one ) Dog_ PNOC ( ortholog_one2one ) GuineaPig_ PNOC ( ortholog_one2one ) Macaque_ PNOC ( ortholog_one2one ) Mouse_ Pnoc ( ortholog_one2one ) Pig_ PNOC ( ortholog_one2one ) Rat_ Pnoc ( ortholog_one2one ) Rabbit_ PNOC ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PDYN, PENK |
| Tissue | appendix, cerebral.cortex, lymph.node, oviduct, spleen, tonsil |
| Tissue Specificity | Predominantly expressed in the brain and spinal cord. Also expressed and secreted by peripheral blood neutrophils following degranulation. {ECO:0000269|PubMed:12950177}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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