| Gene Information | |
|---|---|
| Gene Name | PNO1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 252 |
| Protein Names | RNA-binding protein PNO1 (Partner of NOB1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000115946 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9NRX1 |
| Gene Card | PNO1 |
| Uniprot ID | Q9NRX1 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.890100809) |
| Ortholog in Animals | Alpaca_ PNO1 ( ortholog_one2one ) Dog_ PNO1 ( ortholog_one2one ) GuineaPig_ PNO1 ( ortholog_one2one ) Mouse_ Pno1 ( ortholog_one2one ) Pig_ PNO1 ( ortholog_one2one ) Rat_ Pno1 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in liver, lung, spleen and kidney. Weakly expressed in thymus, testis and ovary. Weakly or not expressed in heart, brain, skeletal muscle, placenta, pancreas, prostate, small intestine, colon and peripheral blood leukocytes. {ECO:0000269|PubMed:15497447}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002230(Rat);0.03937(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6G18 (EM 3.60A ) 6G4S (EM 4.00A ) 6G4W (EM 4.50A ) 6G51 (EM 4.10A ) 6G53 (EM 4.50A ) 6G5I (EM 3.50A ) 6ZUO (EM 3.10A ) 6ZXD (EM 3.20A ) 6ZXE (EM 3.00A ) 7MQ8 (EM 3.60A ) 7MQ9 (EM 3.87A ) 7MQA (EM 2.70A ) |
| DBSNP | rs2044693 rs7590838 |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000269|PubMed:15497447}. |
| Mouse PG classification | NA |
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