| Gene Information | |
|---|---|
| Gene Name | ARID1A |
| Organism | Homo sapiens (Human) |
| Gene Length | 2285 |
| Protein Names | AT-rich interactive domain-containing protein 1A (ARID domain-containing protein 1A) (B120) (BRG1-associated factor 250) (BAF250) (BRG1-associated factor 250a) (BAF250A) (Osa homolog 1) (hOSA1) (SWI-like protein) (SWI/SNF complex protein p270) (SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin subfamily F member 1) (hELD) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000117713 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O14497 |
| Gene Card | ARID1A |
| Uniprot ID | O14497 |
| Pfam | PF01388; PF12031 |
| In ASD | no |
| Allosteric Prediction | no (-0.313252038) |
| Ortholog in Animals | Alpaca_ ARID1A ( ortholog_one2one ) Dog_ ARID1A ( ortholog_one2one ) GuineaPig_ ARID1A ( ortholog_one2one ) Macaque_ ARID1A ( ortholog_one2one ) Mouse_ Arid1a ( ortholog_one2one ) Pig_ ARID1A ( ortholog_one2one ) Rat_ Arid1a ( ortholog_one2one ) Rabbit_ ARID1A ( ortholog_one2one ) |
| Ohnologs | ARID1B |
| Paralogs | ARID1B |
| Tissue | NA |
| Tissue Specificity | Highly expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, and PBL, and at a much lower level in heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas. {ECO:0000269|PubMed:11073988, ECO:0000269|PubMed:11318604, ECO:0000269|PubMed:12200431}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.094687(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
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| PDB | 1RYU (NMR - ) 6LTH (EM 3.00A ) 6LTJ (EM 3.70A ) |
| DBSNP | rs571264557 rs1442666063 rs139230162 rs1553153748 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00355, ECO:0000269|PubMed:11318604, ECO:0000269|PubMed:26614907}. |
| Mouse PG classification | LPG |
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