| Gene Information | |
|---|---|
| Gene Name | IFT140 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1462 |
| Protein Names | Intraflagellar transport protein 140 homolog (WD and tetratricopeptide repeats protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000187535 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96RY7 |
| Gene Card | IFT140 |
| Uniprot ID | Q96RY7 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.887585229) |
| Ortholog in Animals | Alpaca_ IFT140 ( ortholog_one2one ) Dog_ IFT140 ( ortholog_one2one ) GuineaPig_ IFT140 ( ortholog_one2one ) Macaque_ IFT140 ( ortholog_one2one ) Mouse_ Ift140 ( ortholog_one2one ) Pig_ IFT140 ( ortholog_one2one ) Rat_ Ift140 ( ortholog_one2one ) Rabbit_ IFT140 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | IFT172 |
| Tissue | brain, testis |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.107416(Chimpanzee);0.146133(Mouse);0.002657(Rat);0.033333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs772757427 rs371077545 rs1403669200 rs148462329 rs35588860 rs201188361 rs539181813 rs4786350 rs35404373 rs8058674 rs431905521 rs387907193 rs1441549097 rs773372123 rs200292484 rs34762152 rs770890983 rs1555491448 rs8060532 rs778311141 rs758052634 rs150903791 rs199826737 rs8050974 rs373111085 rs11648609 rs781117803 rs387907192 rs34900355 rs34535263 rs144938800 rs751323480 rs767213195 rs145549969 rs745576178 rs2235638 rs200065348 rs146666187 rs431905520 rs559371453 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:22503633, ECO:0000269|PubMed:26968735}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:23418020}. Cell projection, cilium {ECO:0000269|PubMed:22503633, ECO:0000269|PubMed:26968735, ECO:0000269|PubMed:27932497}. |
| Mouse PG classification | NA |
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