| Gene Information | |
|---|---|
| Gene Name | IL17RA |
| Organism | Homo sapiens (Human) |
| Gene Length | 866 |
| Protein Names | Interleukin-17 receptor A (IL-17 receptor A) (IL-17RA) (CDw217) (CD antigen CD217) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000177663 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96F46 |
| Gene Card | IL17RA |
| Uniprot ID | Q96F46 |
| Pfam | PF16556; PF08357 |
| In ASD | no |
| Allosteric Prediction | no (-0.770306392) |
| Ortholog in Animals | Alpaca_ IL17RA ( ortholog_one2one ) GuineaPig_ IL17RA ( ortholog_one2one ) Macaque_ IL17RA ( ortholog_one2one ) Mouse_ Il17ra ( ortholog_one2one ) Pig_ IL17RA ( ortholog_one2one ) Rat_ Il17ra ( ortholog_one2one ) Rabbit_ IL17RA ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | IL17RB, IL17RE, IL17RD, IL17RC |
| Tissue | NA |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:21993848}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002657(Rat);0.033333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3JVF (X-ray 3.30A ) 4HSA (X-ray 3.15A ) 4NUX (X-ray 2.30A ) 5N9B (X-ray 1.90A ) 5NAN (X-ray 3.30A ) 7UWL (EM 3.70A ) 7UWM (EM 2.50A ) 7UWN (EM 3.01A ) |
| DBSNP | rs879577 rs12484684 rs17850765 |
| Subcellular location [CC] | [Isoform 1]: Cell membrane {ECO:0000269|PubMed:17911633}; Single-pass type I membrane protein {ECO:0000255}.; [Isoform 2]: Secreted {ECO:0000269|PubMed:24084331}. |
| Mouse PG classification | NA |
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