| Gene Information | |
|---|---|
| Gene Name | ARMC12 |
| Organism | Homo sapiens (Human) |
| Gene Length | 340 |
| Protein Names | Armadillo repeat-containing protein 12 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000157343 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q5T9G4 |
| Gene Card | ARMC12 |
| Uniprot ID | Q5T9G4 |
| Pfam | PF04826 |
| In ASD | no |
| Allosteric Prediction | no (-1.237231354) |
| Ortholog in Animals | Alpaca_ ARMC12 ( ortholog_one2one ) Dog_ ARMC12 ( ortholog_one2one ) GuineaPig_ ARMC12 ( ortholog_one2one ) Macaque_ ARMC12 ( ortholog_one2one ) Mouse_ Armc12 ( ortholog_one2one ) Pig_ ARMC12 ( ortholog_one2one ) Rat_ Armc12 ( ortholog_one2one ) Rabbit_ ARMC12 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ARMCX2, GPRASP2, ARMCX4, ARMCX1, ARMCX5, GPRASP1, ARMCX3, ARMC10, ARMCX6, ARMCX5-GPRASP2, BHLHB9 |
| Tissue | testis |
| Tissue Specificity | Testis-specific (PubMed:33536340). Expressed at higher levels in neuroblastoma tissues and cell lines, than those of normal dorsal ganglia (at protein level) (PubMed:30026490). Expressed in breast cancer, colon cancer, hepatocellular carcinoma, lung cancer, pancreas cancer, prostate cancer, renal cancer and gastric cancer, but not in their normal counterparts (PubMed:30026490). {ECO:0000269|PubMed:30026490, ECO:0000269|PubMed:33536340}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:30026490}. Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q80X86}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q80X86}. |
| Mouse PG classification | NA |
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