| Gene Information | |
|---|---|
| Gene Name | DDX18 |
| Organism | Homo sapiens (Human) |
| Gene Length | 670 |
| Protein Names | ATP-dependent RNA helicase DDX18 (EC 3.6.4.13) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000088205 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9NVP1 |
| Gene Card | DDX18 |
| Uniprot ID | Q9NVP1 |
| Pfam | PF00270; PF13959; PF00271 |
| In ASD | no |
| Allosteric Prediction | no (-0.657348733) |
| Ortholog in Animals | Alpaca_ DDX18 ( ortholog_one2one ) Dog_ DDX18 ( ortholog_one2one ) GuineaPig_ DDX18 ( ortholog_one2one ) Macaque_ DDX18 ( ortholog_one2one ) Mouse_ Ddx18 ( ortholog_one2one ) Pig_ DDX18 ( ortholog_one2one ) Rabbit_ DDX18 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DDX28, DDX42, DDX25, DDX47, DDX49, DDX20, DDX50, DDX41, DDX24, TDRD12, DDX5, DDX52, DDX56, DDX3X, DDX3Y, DDX59, DDX39B, DDX23, EIF4A3, DDX54, DDX10, DDX19A, DDX19B, EIF4A1, DDX6, DDX39A, DDX55, DDX21, DDX4, DDX1, DDX53, DDX17, DDX31, DDX51, DDX43, EIF4A2, DDX27, DDX46 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.304542(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3LY5 (X-ray 2.80A ) |
| DBSNP | rs1052637 rs10179772 |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000269|PubMed:16963496}. Chromosome {ECO:0000269|PubMed:20813266}. |
| Mouse PG classification | NA |
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