| Gene Information | |
|---|---|
| Gene Name | POU6F1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 301 |
| Protein Names | POU domain, class 6, transcription factor 1 (Brain-specific homeobox/POU domain protein 5) (Brain-5) (Brn-5) (mPOU homeobox protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000184271 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q14863 |
| Gene Card | POU6F1 |
| Uniprot ID | Q14863 |
| Pfam | PF00046; PF00157 |
| In ASD | no |
| Allosteric Prediction | no (-1.816336767) |
| Ortholog in Animals | Alpaca_ POU6F1 ( ortholog_one2one ) Dog_ POU6F1 ( ortholog_one2one ) Macaque_ POU6F1 ( ortholog_one2one ) Mouse_ Pou6f1 ( ortholog_one2one ) Pig_ POU6F1 ( ortholog_one2one ) Rat_ Pou6f1 ( ortholog_one2many ) Rabbit_ POU6F1 ( ortholog_one2one ) |
| Ohnologs | POU6F2 |
| Paralogs | POU1F1, POU2F3, POU4F3, POU3F3, POU4F1, CCDC160, HDX, POU5F1B, POU5F1, POU2F1, POU3F1, POU5F2, POU4F2, POU6F2, POU2F2, POU3F2, POU3F4 |
| Tissue | NA |
| Tissue Specificity | In the embryo, expressed exclusively in the developing brain, whereas in the adult its expression is restricted to brain, heart, skeletal muscle and lung. In the brain, the highest expression levels are found in specific cell layers of the cortex, the olfactory bulb, the hippocampus and the cerebellum. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3D1N (X-ray 2.51A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | NA |
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