| Gene Information | |
|---|---|
| Gene Name | DPP3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 737 |
| Protein Names | Dipeptidyl peptidase 3 (EC 3.4.14.4) (Dipeptidyl aminopeptidase III) (Dipeptidyl arylamidase III) (Dipeptidyl peptidase III) (DPP III) (Enkephalinase B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000254986 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9NY33 |
| Gene Card | DPP3 |
| Uniprot ID | Q9NY33 |
| Pfam | PF03571 |
| In ASD | no |
| Allosteric Prediction | no (-0.029836194) |
| Ortholog in Animals | Alpaca_ DPP3 ( ortholog_one2one ) Dog_ DPP3 ( ortholog_one2one ) GuineaPig_ DPP3 ( ortholog_one2one ) Macaque_ DPP3 ( ortholog_one2one ) Mouse_ Dpp3 ( ortholog_one2one ) Pig_ DPP3 ( ortholog_one2one ) Rat_ Dpp3 ( ortholog_one2one ) Rabbit_ DPP3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Detected in placenta (at protein level) (PubMed:3233187). Detected in erythrocytes (at protein level) (PubMed:1515063). {ECO:0000269|PubMed:1515063, ECO:0000269|PubMed:3233187}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3FVY (X-ray 1.90A ) 3T6B (X-ray 2.40A ) 3T6J (X-ray 2.98A ) 5E2Q (X-ray 2.40A ) 5E33 (X-ray 1.84A ) 5E3A (X-ray 2.05A ) 5E3C (X-ray 2.77A ) 5EGY (X-ray 2.74A ) 5EHH (X-ray 2.38A ) 7OUP (X-ray 2.65A ) |
| DBSNP | rs11826683 rs11550299 rs2305535 rs12421620 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:1515063, ECO:0000269|PubMed:3233187}. |
| Mouse PG classification | NA |
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