| Gene Information | |
|---|---|
| Gene Name | POU4F1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 419 |
| Protein Names | POU domain, class 4, transcription factor 1 (Brain-specific homeobox/POU domain protein 3A) (Brain-3A) (Brn-3A) (Homeobox/POU domain protein RDC-1) (Oct-T1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 55 ( ENSG00000152192 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q01851 |
| Gene Card | POU4F1 |
| Uniprot ID | Q01851 |
| Pfam | PF00046; PF00157 |
| In ASD | no |
| Allosteric Prediction | no (-0.741218752) |
| Ortholog in Animals | Alpaca_ POU4F1 ( ortholog_one2one ) Dog_ POU4F1 ( ortholog_one2one ) Macaque_ POU4F1 ( ortholog_one2one ) Mouse_ Pou4f1 ( ortholog_one2one ) Pig_ POU4F1 ( ortholog_one2one ) Rat_ Pou4f1 ( ortholog_one2one ) Rabbit_ POU4F1 ( ortholog_one2one ) |
| Ohnologs | POU4F3, POU4F2 |
| Paralogs | POU1F1, POU2F3, POU4F3, POU3F3, POU6F1, CCDC160, HDX, POU5F1B, POU5F1, POU2F1, POU3F1, POU5F2, POU4F2, POU6F2, POU2F2, POU3F2, POU3F4 |
| Tissue | NA |
| Tissue Specificity | Expressed in the brain and the retina. Present in the developing brain, spinal cord and eye. {ECO:0000269|PubMed:1357630, ECO:0000269|PubMed:7623109}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1874704791 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:12934100}. Cytoplasm {ECO:0000250|UniProtKB:P17208}. |
| Mouse PG classification | NA |
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