| Gene Information | |
|---|---|
| Gene Name | PMP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 132 |
| Protein Names | Myelin P2 protein (Peripheral myelin protein 2) |
| Target Name | myelin p2 protein |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000147588 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P02689 |
| Gene Card | PMP2 |
| Uniprot ID | P02689 |
| Pfam | PF00061 |
| In ASD | no |
| Allosteric Prediction | no (-1.145256631) |
| Ortholog in Animals | Alpaca_ PMP2 ( ortholog_one2one ) Dog_ PMP2 ( ortholog_one2one ) GuineaPig_ PMP2 ( ortholog_one2one ) Macaque_ PMP2 ( ortholog_one2one ) Mouse_ Pmp2 ( ortholog_one2one ) Pig_ PMP2 ( ortholog_one2one ) Rat_ Pmp2 ( ortholog_one2one ) |
| Ohnologs | CRABP1, FABP3, FABP7 |
| Paralogs | CRABP1, FABP9, FABP5, FABP12, RBP1, FABP4, RBP2, RBP5, RBP7, FABP3, FABP2, FABP6, FABP7, FABP1, CRABP2 |
| Tissue | brain, cerebral.cortex |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
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| PDB | 2WUT (X-ray 1.85A ) 3NR3 (X-ray 1.95A ) 4A1H (X-ray 2.20A ) 4A1Y (X-ray 1.20A ) 4A8Z (X-ray 1.80A ) 4BVM (X-ray 0.93A ) 4D6A (X-ray 1.45A ) 4D6B (X-ray 2.12A ) 5N4M (X-ray 1.59A ) 5N4P (X-ray 1.53A ) 5N4Q (X-ray 1.72A ) 6EW2 (X-ray 1.59A ) 6EW4 (X-ray 1.27A ) 6EW5 (X-ray 1.95A ) 6S2M (X-ray 0.72A ) 6S2S (X-ray 0.86A ) 6STS (X-ray 3.00A ) 6XU5 (X-ray 1.65A ) 6XU9 (X-ray 2.70A ) 6XUA (X-ray 2.30A ) 6XUW (X-ray 2.31A ) 6XVQ (X-ray 1.80A ) 6XVR (X-ray 2.00A ) 6XVS (X-ray 1.80A ) 6XVY (X-ray 1.80A ) 6XW9 (X-ray 2.90A ) 7NRW (X-ray 2.00A ) 7NSR (X-ray 1.50A ) 7NTP (X-ray 2.10A ) 7O60 (Other 2.00A ) |
| DBSNP | rs879253869 rs1563518390 rs1563518388 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. |
| Mouse PG classification | NA |
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