Gene Information
Gene NameSTOX1
OrganismHomo sapiens (Human)
Gene Length989
Protein NamesStorkhead-box protein 1 (Winged-helix domain-containing protein)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000165730 )
Evolutionary StageEumetazoa
AlphaFoldDBQ6ZVD7
Gene CardSTOX1
Uniprot IDQ6ZVD7
PfamPF10264
In ASDno
Allosteric Predictionno (-0.850643819)
Ortholog in AnimalsAlpaca_ STOX1 ( ortholog_one2one )
Dog_ STOX1 ( ortholog_one2one )
GuineaPig_ STOX1 ( ortholog_one2one )
Macaque_ STOX1 ( ortholog_one2one )
Mouse_ Stox1 ( ortholog_one2one )
Pig_ STOX1 ( ortholog_one2one )
Rat_ Stox1 ( ortholog_one2one )
Rabbit_ STOX1 ( ortholog_one2one )
OhnologsSTOX2
ParalogsSTOX2
TissueNA
Tissue SpecificityExpressed in placenta, including the invasive extravillus trophoblast cells. {ECO:0000269|PubMed:15806103}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs556362193  rs1341667  rs10509305  rs41278532  rs7904300 
Subcellular location [CC][Isoform A]: Cytoplasm {ECO:0000269|PubMed:22253775}. Nucleus {ECO:0000269|PubMed:22253775}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:22253775}. Note=In epithelial cells, diffusely expressed in the cytoplasm, particularly in peri-membrane cortical regions (By similarity). Concentrated at centrosomes during metaphase (PubMed:22253775). {ECO:0000250|UniProtKB:B2RQL2, ECO:0000269|PubMed:22253775}.;
[Isoform B]: Nucleus.;
[Isoform C]: Nucleus, nucleolus.
Mouse PG classificationNA
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