| Gene Information | |
|---|---|
| Gene Name | KDM3A |
| Organism | Homo sapiens (Human) |
| Gene Length | 1321 |
| Protein Names | Lysine-specific demethylase 3A (EC 1.14.11.65) (JmjC domain-containing histone demethylation protein 2A) (Jumonji domain-containing protein 1A) ([histone H3]-dimethyl-L-lysine(9) demethylase 3A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000115548 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9Y4C1 |
| Gene Card | KDM3A |
| Uniprot ID | Q9Y4C1 |
| Pfam | PF02373 |
| In ASD | no |
| Allosteric Prediction | yes (0.307346227) |
| Ortholog in Animals | Alpaca_ KDM3A ( ortholog_one2one ) Dog_ KDM3A ( ortholog_one2one ) GuineaPig_ KDM3A ( ortholog_one2one ) Macaque_ KDM3A ( ortholog_one2one ) Mouse_ Kdm3a ( ortholog_one2one ) Pig_ KDM3A ( ortholog_one2one ) Rat_ Kdm3a ( ortholog_one2one ) Rabbit_ KDM3A ( ortholog_one2one ) |
| Ohnologs | KDM3B, JMJD1C |
| Paralogs | JMJD1C, HR, KDM3B |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs13424350 rs2030259 rs34605051 rs11677451 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Nuclear in round spermatids. When spermatids start to elongate, localizes to the cytoplasm where it forms distinct foci which disappear in mature spermatozoa (By similarity). {ECO:0000250}. |
| Mouse PG classification | NA |
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