| Gene Information | |
|---|---|
| Gene Name | PMFBP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1007 |
| Protein Names | Polyamine-modulated factor 1-binding protein 1 (PMF-1-binding protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 424 ( ENSG00000118557 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q8TBY8 |
| Gene Card | PMFBP1 |
| Uniprot ID | Q8TBY8 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.740582678) |
| Ortholog in Animals | Alpaca_ PMFBP1 ( ortholog_one2one ) Dog_ PMFBP1 ( ortholog_one2one ) GuineaPig_ PMFBP1 ( ortholog_one2one ) Macaque_ PMFBP1 ( ortholog_one2one ) Mouse_ Pmfbp1 ( ortholog_one2one ) Pig_ PMFBP1 ( ortholog_one2one ) Rat_ Pmfbp1 ( ortholog_one2one ) Rabbit_ PMFBP1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | testis |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs217180 rs35370634 rs35781168 rs34832584 rs34832584 rs16973716 rs17852563 |
| Subcellular location [CC] | Cell projection, cilium, flagellum {ECO:0000269|PubMed:30032984, ECO:0000269|PubMed:30298696}. Note=Localized at the sperm head-tail connecting piece (PubMed:30032984, PubMed:30298696). During spermatogenesis, it is first observed in the cytoplasm of round spermatids, it later appears in the implantation fossa region of the sperm nucleus during sperm head elongation and differentiation, and finally it localizes to the head-tail connecting piece (By similarity). {ECO:0000250|UniProtKB:Q9WVQ0, ECO:0000269|PubMed:30032984, ECO:0000269|PubMed:30298696}. |
| Mouse PG classification | NA |
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