| Gene Information | |
|---|---|
| Gene Name | BCAM |
| Organism | Homo sapiens (Human) |
| Gene Length | 628 |
| Protein Names | Basal cell adhesion molecule (Auberger B antigen) (B-CAM cell surface glycoprotein) (F8/G253 antigen) (Lutheran antigen) (Lutheran blood group glycoprotein) (CD antigen CD239) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000187244 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P50895 |
| Gene Card | BCAM |
| Uniprot ID | P50895 |
| Pfam | PF08205; PF13895; PF07686 |
| In ASD | no |
| Allosteric Prediction | no (-1.23062688) |
| Ortholog in Animals | Alpaca_ BCAM ( ortholog_one2one ) Dog_ BCAM ( ortholog_one2one ) GuineaPig_ BCAM ( ortholog_one2one ) Macaque_ BCAM ( ortholog_one2one ) Mouse_ Bcam ( ortholog_one2one ) Pig_ BCAM ( ortholog_one2one ) Rat_ Bcam ( ortholog_one2one ) |
| Ohnologs | MCAM, ALCAM |
| Paralogs | AGER, MCAM, ALCAM |
| Tissue | NA |
| Tissue Specificity | Wide tissue distribution (highest in the pancreas and very low in brain). Closely associated with the basal layer of cells in epithelia and the endothelium of blood vessel walls. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2PET (X-ray 1.70A ) 2PF6 (X-ray 2.20A ) |
| DBSNP | rs28399653 rs28399654 rs28399656 rs9967601 rs28399626 rs28399630 rs1135062 rs28399659 |
| Subcellular location [CC] | Membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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