| Gene Information | |
|---|---|
| Gene Name | ATP1A2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1020 |
| Protein Names | Sodium/potassium-transporting ATPase subunit alpha-2 (Na(+)/K(+) ATPase alpha-2 subunit) (EC 7.2.2.13) (Sodium pump subunit alpha-2) |
| Target Name | sodium/potassium transporting atpase subunits |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000018625 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P50993 |
| Gene Card | ATP1A2 |
| Uniprot ID | P50993 |
| Pfam | PF00689; PF00690 |
| In ASD | no |
| Allosteric Prediction | yes (1.165321959) |
| Ortholog in Animals | Alpaca_ ATP1A2 ( ortholog_one2one ) Dog_ ATP1A4 ( ortholog_one2one ) GuineaPig_ ATP1A2 ( ortholog_one2one ) Mouse_ Atp1a2 ( ortholog_one2one ) Pig_ ATP1A2 ( ortholog_one2one ) Rat_ Atp1a2 ( ortholog_one2one ) Rabbit_ ATP1A2 ( ortholog_one2one ) |
| Ohnologs | ATP1A3, ATP1A1 |
| Paralogs | ATP2B4, ATP13A3, ATP7A, ATP2A3, ATP2B3, ATP1A3, ATP13A2, ATP2B2, ATP13A4, ATP7B, ATP13A5, ATP12A, ATP2B1, ATP1A4, ATP2C2, ATP1A1, ATP2A1, ATP2A2, ATP4A, ATP2C1, ATP13A1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002990(Rat);0.02(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1553244746 rs1057521630 rs1057518514 rs28934002 rs1553245178 rs886039530 rs28933401 rs1553245771 rs28933400 rs28933398 rs28933399 rs746795369 |
| Subcellular location [CC] | Membrane {ECO:0000269|PubMed:7711835}; Multi-pass membrane protein {ECO:0000269|PubMed:7711835}. Cell membrane {ECO:0000269|PubMed:7711835}; Multi-pass membrane protein {ECO:0000269|PubMed:7711835}. |
| Mouse PG classification | LPG |
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