| Gene Information | |
|---|---|
| Gene Name | PNPLA7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1317 |
| Protein Names | Patatin-like phospholipase domain-containing protein 7 (EC 3.1.1.-) (EC 3.1.1.5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000130653 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q6ZV29 |
| Gene Card | PNPLA7 |
| Uniprot ID | Q6ZV29 |
| Pfam | PF00027; PF01734 |
| In ASD | no |
| Allosteric Prediction | no (-0.439012042) |
| Ortholog in Animals | Alpaca_ PNPLA7 ( ortholog_one2one ) Dog_ PNPLA7 ( ortholog_one2one ) GuineaPig_ PNPLA7 ( ortholog_one2one ) Macaque_ PNPLA7 ( ortholog_one2one ) Mouse_ Pnpla7 ( ortholog_one2one ) Pig_ PNPLA7 ( ortholog_one2one ) Rat_ Pnpla7 ( ortholog_one2one ) Rabbit_ PNPLA7 ( ortholog_one2one ) |
| Ohnologs | PNPLA6 |
| Paralogs | PNPLA6 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12788 rs2298171 rs11137410 rs3750378 rs3750379 rs11791683 rs1891630 rs34938599 rs3812499 rs35177111 rs4962237 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:A2AJ88}; Single-pass type III membrane protein {ECO:0000250|UniProtKB:A2AJ88}. Lipid droplet {ECO:0000250|UniProtKB:A2AJ88}. |
| Mouse PG classification | NA |
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