| Gene Information | |
|---|---|
| Gene Name | PLSCR4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 329 |
| Protein Names | Phospholipid scramblase 4 (PL scramblase 4) (Ca(2+)-dependent phospholipid scramblase 4) (Cell growth-inhibiting gene 43 protein) (TRA1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000114698 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9NRQ2 |
| Gene Card | PLSCR4 |
| Uniprot ID | Q9NRQ2 |
| Pfam | PF03803 |
| In ASD | no |
| Allosteric Prediction | no (-0.770602863) |
| Ortholog in Animals | Alpaca_ PLSCR4 ( ortholog_one2one ) Dog_ PLSCR4 ( ortholog_one2one ) GuineaPig_ PLSCR4 ( ortholog_one2one ) Macaque_ PLSCR4 ( ortholog_one2one ) Mouse_ Plscr4 ( ortholog_one2one ) Pig_ PLSCR4 ( ortholog_one2one ) Rat_ Plscr4 ( ortholog_one2one ) Rabbit_ PLSCR4 ( ortholog_one2one ) |
| Ohnologs | PLSCR3 |
| Paralogs | PLSCR1, PLSCR5, PLSCR3, PLSCR2 |
| Tissue | NA |
| Tissue Specificity | Expressed in heart, brain, placenta, lung, liver, kidney, pancreas, spleen, thymus, prostate, testis, uterus, small intestine and colon. Not detected in peripheral blood lymphocytes. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3Q5U (X-ray 2.50A ) |
| DBSNP | rs3762685 rs1061409 |
| Subcellular location [CC] | Membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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