Gene Information
Gene NamePLSCR2
OrganismHomo sapiens (Human)
Gene Length297
Protein NamesPhospholipid scramblase 2 (PL scramblase 2) (Ca(2+)-dependent phospholipid scramblase 2)
Target NameNA
Target TypeNA
Gene Age55 ( ENSG00000163746 )
Evolutionary StageEumetazoa
AlphaFoldDBQ9NRY7
Gene CardPLSCR2
Uniprot IDQ9NRY7
PfamPF03803
In ASDno
Allosteric Predictionno (-0.936498844)
Ortholog in AnimalsAlpaca_ PLSCR2 ( ortholog_one2one )
Macaque_ PLSCR2 ( ortholog_one2one )
OhnologsPLSCR3
ParalogsPLSCR4, PLSCR1, PLSCR5, PLSCR3
Tissuetestis
Tissue SpecificityExpression of isoform 1 seems restricted to testis. {ECO:0000269|PubMed:10930526}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Membrane {ECO:0000250};
Single-pass type II membrane protein {ECO:0000250}.;
[Isoform 1]: Nucleus {ECO:0000269|PubMed:24648509}.
Mouse PG classificationNA
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