| Gene Information | |
|---|---|
| Gene Name | PLS1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 629 |
| Protein Names | Plastin-1 (Intestine-specific plastin) (I-plastin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000120756 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q14651 |
| Gene Card | PLS1 |
| Uniprot ID | Q14651 |
| Pfam | PF00307; PF13499 |
| In ASD | no |
| Allosteric Prediction | no (-0.374036075) |
| Ortholog in Animals | Alpaca_ PLS1 ( ortholog_one2one ) Dog_ PLS1 ( ortholog_one2one ) GuineaPig_ PLS1 ( ortholog_one2one ) Macaque_ PLS1 ( ortholog_one2one ) Mouse_ Pls1 ( ortholog_one2one ) Pig_ PLS1 ( ortholog_one2one ) Rat_ Pls1 ( ortholog_one2one ) Rabbit_ PLS1 ( ortholog_one2one ) |
| Ohnologs | PLS3, LCP1 |
| Paralogs | LCP1, PLS3 |
| Tissue | small.intestine.Peyers.patch, transverse.colon |
| Tissue Specificity | In small intestine, colon, and kidney; relatively lower levels of expression are detected in the lung and stomach. {ECO:0000269|PubMed:8139549}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.04(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35710125 rs35435507 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:Q3V0K9}. Cell projection, stereocilium {ECO:0000250|UniProtKB:Q3V0K9}. |
| Mouse PG classification | NA |
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