| Gene Information | |
|---|---|
| Gene Name | PLPPR5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 321 |
| Protein Names | Phospholipid phosphatase-related protein type 5 (Lipid phosphate phosphatase-related protein type 5) (Phosphatidic acid phosphatase type 2d) (Plasticity-related gene 5 protein) (PRG-5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000117598 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q32ZL2 |
| Gene Card | PLPPR5 |
| Uniprot ID | Q32ZL2 |
| Pfam | PF01569 |
| In ASD | no |
| Allosteric Prediction | no (-1.183185976) |
| Ortholog in Animals | Alpaca_ PLPPR5 ( ortholog_one2one ) Dog_ PLPPR5 ( ortholog_one2one ) GuineaPig_ PLPPR5 ( ortholog_one2one ) Macaque_ PLPPR5 ( ortholog_one2one ) Mouse_ Plppr5 ( ortholog_one2one ) Pig_ PLPPR5 ( ortholog_one2one ) Rat_ Plppr5 ( ortholog_one2one ) Rabbit_ PLPPR5 ( ortholog_one2one ) |
| Ohnologs | PLPPR2, PLPPR3, PLPP2, PLPPR1 |
| Paralogs | PLPPR1, PLPPR4, PLPP3, PLPP4, PLPP2, PLPPR3, PLPPR2, PLPP1, PLPP5 |
| Tissue | brain, pineal.gland |
| Tissue Specificity | Isoform 1 is expressed in brain, lung, kidney and colon. Isoform 2 is expressed in placenta, skeletal muscle and kidney. {ECO:0000269|PubMed:16010976}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000250|UniProtKB:Q8BJ52}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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