| Gene Information | |
|---|---|
| Gene Name | BCAS1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 584 |
| Protein Names | Breast carcinoma-amplified sequence 1 (Amplified and overexpressed in breast cancer) (Novel amplified in breast cancer 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000064787 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | O75363 |
| Gene Card | BCAS1 |
| Uniprot ID | O75363 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.932802813) |
| Ortholog in Animals | Alpaca_ BCAS1 ( ortholog_one2one ) Dog_ BCAS1 ( ortholog_one2one ) GuineaPig_ BCAS1 ( ortholog_one2one ) Macaque_ BCAS1 ( ortholog_one2one ) Mouse_ Bcas1 ( ortholog_one2one ) Pig_ BCAS1 ( ortholog_one2one ) Rat_ Bcas1 ( ortholog_one2one ) Rabbit_ BCAS1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | colon, gall.bladder, prostate, brain, small.intestine |
| Tissue Specificity | Highly expressed in the brain and, more specifically, in oligodendrocytes (at protein level). Expressed in the prostate, and at lower levels in testis, intestine and colon. Overexpressed in most breast cancer cell lines and down-regulated in some colorectal tumors. {ECO:0000269|PubMed:10857754, ECO:0000269|PubMed:14567997, ECO:0000269|PubMed:29212715}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs394732 rs158551 rs6022903 rs35575210 rs1055246 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:14567997}. |
| Mouse PG classification | NA |
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