| Gene Information | |
|---|---|
| Gene Name | PLPP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 288 |
| Protein Names | Phospholipid phosphatase 2 (EC 3.1.3.-) (EC 3.1.3.4) (Lipid phosphate phosphohydrolase 2) (PAP2-gamma) (PAP2-G) (Phosphatidate phosphohydrolase type 2c) (Phosphatidic acid phosphatase 2c) (PAP-2c) (PAP2c) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000141934 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O43688 |
| Gene Card | PLPP2 |
| Uniprot ID | O43688 |
| Pfam | PF01569 |
| In ASD | no |
| Allosteric Prediction | no (-0.83382403) |
| Ortholog in Animals | Alpaca_ PLPP2 ( ortholog_one2one ) GuineaPig_ PLPP2 ( ortholog_one2one ) Mouse_ Plpp2 ( ortholog_one2one ) Pig_ PLPP2 ( ortholog_one2one ) Rat_ Plpp2 ( ortholog_one2one ) Rabbit_ PLPP2 ( ortholog_one2one ) |
| Ohnologs | PLPP1, PLPPR5, PLPPR1, PLPP3 |
| Paralogs | PLPPR5, PLPPR1, PLPPR4, PLPP3, PLPP4, PLPPR3, PLPPR2, PLPP1, PLPP5 |
| Tissue | NA |
| Tissue Specificity | Found mainly in brain, pancreas and placenta. {ECO:0000269|PubMed:9607309}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1138439 |
| Subcellular location [CC] | Membrane {ECO:0000269|PubMed:16467304, ECO:0000269|PubMed:9705349}; Multi-pass membrane protein {ECO:0000255}. Cell membrane {ECO:0000269|PubMed:16467304, ECO:0000269|PubMed:9705349}; Multi-pass membrane protein {ECO:0000255}. Early endosome membrane {ECO:0000269|PubMed:16467304}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:16467304}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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