| Gene Information | |
|---|---|
| Gene Name | PLOD1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 727 |
| Protein Names | Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 (EC 1.14.11.4) (Lysyl hydroxylase 1) (LH1) |
| Target Name | procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000083444 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q02809 |
| Gene Card | PLOD1 |
| Uniprot ID | Q02809 |
| Pfam | PF03171 |
| In ASD | no |
| Allosteric Prediction | yes (0.179533114) |
| Ortholog in Animals | Alpaca_ PLOD1 ( ortholog_one2one ) Dog_ PLOD1 ( ortholog_one2one ) GuineaPig_ PLOD1 ( ortholog_one2one ) Macaque_ PLOD1 ( ortholog_one2one ) Mouse_ Plod1 ( ortholog_one2one ) Pig_ PLOD1 ( ortholog_one2one ) Rat_ Plod1 ( ortholog_one2one ) Rabbit_ PLOD1 ( ortholog_one2one ) |
| Ohnologs | PLOD3, PLOD2 |
| Paralogs | PLOD2, PLOD3, CERCAM, COLGALT2, COLGALT1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs7551068 rs34878020 rs7551175 rs2273285 rs1645691361 rs797044446 rs121913553 rs199730384 rs121913551 |
| Subcellular location [CC] | Rough endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side. |
| Mouse PG classification | NA |
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