| Gene Information | |
|---|---|
| Gene Name | DCNP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 244 |
| Protein Names | Dendritic cell nuclear protein 1 (Dendritic cell nuclear protein-1) (Dendritic cell-associated nuclear protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8TF63 |
| Gene Card | DCANP1 |
| Uniprot ID | Q8TF63 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in neurons of the paraventricular nucleus, thalamus and occipital cortex and in glial cells (at protein level). Predominantly expressed in dendritic cells. Detected in brain and skeletal muscle. Highly expressed in mature dendritic cells and at a lower level in immature dendritic cells. Expressed in paraventricular nucleus, supraoptic nucleus and nucleus basalis of Meynert. Strongly expressed in paraventricular nucleus of depressed patients compared to controls. Not expressed in monocytes and B-cells. {ECO:0000269|PubMed:11798177, ECO:0000269|PubMed:20693543}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1031844 rs12520809 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:11798177, ECO:0000269|PubMed:20693543}. Cytoplasm {ECO:0000269|PubMed:20693543}. Note=Particularly on the periphery. Colocalizes with corticotropin-releasing hormone (CRH) in parvocellular neurons in the paraventricular nucleus. {ECO:0000269|PubMed:20693543}. |
| Mouse PG classification | NA |
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