| Gene Information | |
|---|---|
| Gene Name | PLIN1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 522 |
| Protein Names | Perilipin-1 (Lipid droplet-associated protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000166819 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O60240 |
| Gene Card | PLIN1 |
| Uniprot ID | O60240 |
| Pfam | PF03036 |
| In ASD | no |
| Allosteric Prediction | no (-0.16544961) |
| Ortholog in Animals | Alpaca_ PLIN1 ( ortholog_one2one ) Dog_ PLIN1 ( ortholog_one2one ) GuineaPig_ PLIN1 ( ortholog_one2one ) Macaque_ PLIN1 ( ortholog_one2one ) Mouse_ Plin1 ( ortholog_one2one ) Pig_ PLIN1 ( ortholog_one2one ) Rat_ Plin1 ( ortholog_one2one ) |
| Ohnologs | PLIN3, PLIN5, PLIN2 |
| Paralogs | PLIN5, PLIN4, PLIN2, PLIN3 |
| Tissue | adipose.tissue, bone.marrow, greater.omentum, subcutaneous.adipose.tissue |
| Tissue Specificity | Detected in adipocytes from white adipose tissue (at protein level) (PubMed:27832861). Detected in visceral adipose tissue and mammary gland (PubMed:9521880). {ECO:0000269|PubMed:27832861, ECO:0000269|PubMed:9521880}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.004323(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6496589 rs17852910 rs58361219 rs8179071 |
| Subcellular location [CC] | Endoplasmic reticulum {ECO:0000269|PubMed:23399566}. Lipid droplet {ECO:0000269|PubMed:23399566, ECO:0000305|PubMed:26357594}. Note=Lipid droplet surface-associated. {ECO:0000269|PubMed:23399566}. |
| Mouse PG classification | LPG |
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