Gene Information
Gene NamePLEKHS1
OrganismHomo sapiens (Human)
Gene Length465
Protein NamesPleckstrin homology domain-containing family S member 1 (PH domain-containing family S member 1) (Epididymis luminal protein 185) (hEL185)
Target NameNA
Target TypeNA
Gene Age332 ( ENSG00000148735 )
Evolutionary StageVertebrata
AlphaFoldDBQ5SXH7
Gene CardPLEKHS1
Uniprot IDQ5SXH7
PfamPF00169
In ASDno
Allosteric Predictionno (-1.217410792)
Ortholog in AnimalsAlpaca_ PLEKHS1 ( ortholog_one2one )
Dog_ PLEKHS1 ( ortholog_one2one )
GuineaPig_ PLEKHS1 ( ortholog_one2one )
Macaque_ PLEKHS1 ( ortholog_one2one )
Mouse_ Plekhs1 ( ortholog_one2one )
Pig_ PLEKHS1 ( ortholog_one2one )
Rabbit_ PLEKHS1 ( ortholog_one2one )
OhnologsNA
ParalogsGAB3, PHLDB2, PHLDB3, GAB1, GAB4, PHLDB1, GAB2
Tissueduodenum, oviduct, pancreas, salivary.gland, small.intestine, stomach, minor.salivary.gland, small.intestine.Peyers.patch
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs34024791 
Subcellular location [CC]NA
Mouse PG classificationNA
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