| Gene Information | |
|---|---|
| Gene Name | KCNAB3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 404 |
| Protein Names | Voltage-gated potassium channel subunit beta-3 (K(+) channel subunit beta-3) (Kv-beta-3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000170049 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | O43448 |
| Gene Card | KCNAB3 |
| Uniprot ID | O43448 |
| Pfam | PF00248 |
| In ASD | no |
| Allosteric Prediction | no (-0.026755055) |
| Ortholog in Animals | Alpaca_ KCNAB3 ( ortholog_one2one ) Dog_ KCNAB3 ( ortholog_one2one ) GuineaPig_ KCNAB3 ( ortholog_one2one ) Macaque_ KCNAB3 ( ortholog_one2one ) Mouse_ Kcnab3 ( ortholog_one2one ) Pig_ KCNAB3 ( ortholog_one2one ) Rat_ Kcnab3 ( ortholog_one2one ) Rabbit_ KCNAB3 ( ortholog_one2one ) |
| Ohnologs | KCNAB2, KCNAB1 |
| Paralogs | AKR1C8, AKR7A3, KCNAB1, AKR7A2, AKR1C3, AKR1C1, AKR1B1, AKR1E2, AKR1C4, AKR1A1, AKR1C2, AKR1B15, AKR1B10, KCNAB2, AKR7L, AKR1D1 |
| Tissue | cerebellar.hemisphere, cerebellum |
| Tissue Specificity | Brain specific. Most prominent expression in cerebellum. Weaker signals detected in cortex, occipital lobe, frontal lobe and temporal lobe. Not detected in spinal cord, heart, lung, liver, kidney, pancreas, placenta and skeletal muscle. {ECO:0000269|PubMed:9857044}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000305}. |
| Mouse PG classification | NA |
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