| Gene Information | |
|---|---|
| Gene Name | PLEKHG3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1219 |
| Protein Names | Pleckstrin homology domain-containing family G member 3 (PH domain-containing family G member 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000126822 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | A1L390 |
| Gene Card | PLEKHG3 |
| Uniprot ID | A1L390 |
| Pfam | PF00169; PF00621 |
| In ASD | no |
| Allosteric Prediction | no (-0.933126923) |
| Ortholog in Animals | Alpaca_ PLEKHG3 ( ortholog_one2one ) Dog_ PLEKHG3 ( ortholog_one2one ) GuineaPig_ PLEKHG3 ( ortholog_one2one ) Macaque_ PLEKHG3 ( ortholog_one2one ) Mouse_ Plekhg3 ( ortholog_one2one ) Pig_ PLEKHG3 ( ortholog_one2one ) Rat_ Plekhg3 ( ortholog_one2one ) Rabbit_ PLEKHG3 ( ortholog_one2one ) |
| Ohnologs | PLEKHG2, PLEKHG1 |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs41309246 rs229649 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000269|PubMed:27555588}. Note=Colocalizes with actin at the leading edge of polarized cells. {ECO:0000269|PubMed:27555588}. |
| Mouse PG classification | NA |
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