| Gene Information | |
|---|---|
| Gene Name | PLEKHB2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 222 |
| Protein Names | Pleckstrin homology domain-containing family B member 2 (PH domain-containing family B member 2) (Evectin-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000115762 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96CS7 |
| Gene Card | PLEKHB2 |
| Uniprot ID | Q96CS7 |
| Pfam | PF00169 |
| In ASD | no |
| Allosteric Prediction | no (-1.69966478) |
| Ortholog in Animals | Alpaca_ PLEKHB2 ( ortholog_one2one ) Dog_ PLEKHB2 ( ortholog_one2one ) GuineaPig_ PLEKHB2 ( ortholog_one2one ) Macaque_ PLEKHB2 ( ortholog_one2one ) Mouse_ Plekhb2 ( ortholog_one2one ) Pig_ PLEKHB2 ( ortholog_one2one ) Rat_ Plekhb2 ( ortholog_one2one ) Rabbit_ PLEKHB2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PLEKHB1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3AJ4 (X-ray 1.00A ) 3VIA (X-ray 1.75A ) |
| DBSNP | NA |
| Subcellular location [CC] | Recycling endosome membrane {ECO:0000269|PubMed:21911378, ECO:0000269|PubMed:22281740}; Peripheral membrane protein {ECO:0000269|PubMed:21911378, ECO:0000269|PubMed:22281740}. Note=Specifically detected in tubulovesicular structures, and colocalizes with TFNR. |
| Mouse PG classification | NA |
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