| Gene Information | |
|---|---|
| Gene Name | PNLIPRP2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 469 |
| Protein Names | Pancreatic lipase-related protein 2 (PL-RP2) (Cytotoxic T lymphocyte lipase) (Galactolipase) (EC 3.1.1.26) (Triacylglycerol lipase) (EC 3.1.1.3) |
| Target Name | pancreatic lipase-related protein 2 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000266200 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P54317 |
| Gene Card | PNLIPRP2 |
| Uniprot ID | P54317 |
| Pfam | PF00151; PF01477 |
| In ASD | no |
| Allosteric Prediction | yes (0.009925836) |
| Ortholog in Animals | Alpaca_ PNLIPRP2 ( ortholog_one2one ) GuineaPig_ PNLIPRP2 ( ortholog_one2one ) Macaque_ PNLIPRP2 ( ortholog_one2one ) Mouse_ Pnliprp2 ( ortholog_one2one ) Pig_ PNLIPRP2 ( ortholog_one2one ) Rat_ Pnliprp2 ( ortholog_one2one ) Rabbit_ PNLIPRP2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PNLIP, PLA1A, PNLIPRP3, LIPI, LIPC, LIPH, PNLIPRP1, LIPG, LPL |
| Tissue | NA |
| Tissue Specificity | Pancreas. {ECO:0000269|PubMed:10674344}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2OXE (X-ray 2.80A ) 2PVS (X-ray 3.00A ) |
| DBSNP | rs4751995 rs4751996 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:18702514, ECO:0000269|PubMed:19824014}. Zymogen granule membrane {ECO:0000250|UniProtKB:P54318}; Peripheral membrane protein {ECO:0000250|UniProtKB:P54318}. Cell projection, neuron projection {ECO:0000250|UniProtKB:P54318}. Note=Localizes to neurite tips in neuronal cells. {ECO:0000250|UniProtKB:P54318}. |
| Mouse PG classification | NA |
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