| Gene Information | |
|---|---|
| Gene Name | MARCHF4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 410 |
| Protein Names | E3 ubiquitin-protein ligase MARCHF4 (EC 2.3.2.27) (Membrane-associated RING finger protein 4) (Membrane-associated RING-CH protein IV) (MARCH-IV) (RING finger protein 174) (RING-type E3 ubiquitin transferase MARCHF4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000144583 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9P2E8 |
| Gene Card | MARCHF4 |
| Uniprot ID | Q9P2E8 |
| Pfam | PF12906 |
| In ASD | no |
| Allosteric Prediction | no (-1.845176087) |
| Ortholog in Animals | Alpaca_ MARCHF4 ( ortholog_one2one ) Dog_ MARCHF4 ( ortholog_one2one ) GuineaPig_ MARCHF4 ( ortholog_one2one ) Macaque_ MARCHF4 ( ortholog_one2one ) Mouse_ Marchf4 ( ortholog_one2one ) Pig_ MARCHF4 ( ortholog_one2one ) Rat_ Marchf4 ( ortholog_one2one ) Rabbit_ MARCHF4 ( ortholog_one2one ) |
| Ohnologs | MARCHF11 |
| Paralogs | MARCHF8, MARCHF9, MARCHF1, MARCHF11, MARCHF3, MARCHF2 |
| Tissue | brain |
| Tissue Specificity | Expressed in brain and placenta. {ECO:0000269|PubMed:14722266}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Golgi apparatus membrane {ECO:0000269|PubMed:14722266}; Multi-pass membrane protein {ECO:0000269|PubMed:14722266}. |
| Mouse PG classification | NA |
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