| Gene Information | |
|---|---|
| Gene Name | MAP3K19 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1328 |
| Protein Names | Mitogen-activated protein kinase kinase kinase 19 (EC 2.7.11.1) (Regulated in COPD, protein kinase) (SPS1/STE20-related protein kinase YSK4) |
| Target Name | sps1/ste20-related protein kinase ysk4 |
| Target Type | Patented-recorded target |
| Gene Age | 645 ( ENSG00000176601 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q56UN5 |
| Gene Card | MAP3K19 |
| Uniprot ID | Q56UN5 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | no (-0.751380834) |
| Ortholog in Animals | Alpaca_ MAP3K19 ( ortholog_one2one ) Dog_ MAP3K19 ( ortholog_one2one ) GuineaPig_ MAP3K19 ( ortholog_one2one ) Macaque_ MAP3K19 ( ortholog_one2one ) Mouse_ Map3k19 ( ortholog_one2one ) Pig_ MAP3K19 ( ortholog_one2one ) Rat_ AABR07020879.1 ( ortholog_one2one ) Rabbit_ MAP3K19 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PAK5, PAK6, PAK4, SBK2, STK39, MAP4K1, PAK2, PAK1, PAK3, MINK1, TNIK, MAP4K5, SLK, MAP3K14, STRADB, STK4, MAP3K1, TAOK2, MAP4K3, NRK, STRADA, MAP2K3, STK10, MAP2K6, STK26, TAOK3, TAOK1, MAP3K8, MAP4K2, OXSR1, STK3, NEK4, STK25, STK24, MAP4K4 |
| Tissue | medulla.oblongata |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs16831235 rs1112542 rs3905317 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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