| Gene Information | |
|---|---|
| Gene Name | DPYSL3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 570 |
| Protein Names | Dihydropyrimidinase-related protein 3 (DRP-3) (Collapsin response mediator protein 4) (CRMP-4) (Unc-33-like phosphoprotein 1) (ULIP-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000113657 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q14195 |
| Gene Card | DPYSL3 |
| Uniprot ID | Q14195 |
| Pfam | PF01979 |
| In ASD | no |
| Allosteric Prediction | no (-1.000464742) |
| Ortholog in Animals | Alpaca_ DPYSL3 ( ortholog_one2one ) Dog_ DPYSL3 ( ortholog_one2one ) GuineaPig_ DPYSL3 ( ortholog_one2one ) Macaque_ DPYSL3 ( ortholog_one2one ) Mouse_ Dpysl3 ( ortholog_one2one ) Pig_ DPYSL3 ( ortholog_one2one ) Rat_ Dpysl3 ( ortholog_one2one ) Rabbit_ DPYSL3 ( ortholog_one2one ) |
| Ohnologs | DPYSL2, DPYS, DPYSL4, CRMP1 |
| Paralogs | CRMP1, DPYSL2, DPYSL4, DPYSL5, DPYS |
| Tissue | NA |
| Tissue Specificity | Mainly expressed in heart and skeletal muscle. Also strongly expressed in fetal brain and spinal cord. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001759(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4BKN (X-ray 2.10A ) 4CNS (X-ray 2.40A ) 4CNT (X-ray 2.65A ) 4CNU (X-ray 2.80A ) |
| DBSNP | rs2304044 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Cell projection, growth cone {ECO:0000250}. Note=Colocalizes with synaptic vesicle protein 2 in the central region of the growth cone. {ECO:0000250}. |
| Mouse PG classification | NA |
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