| Gene Information | |
|---|---|
| Gene Name | PLB1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1458 |
| Protein Names | Phospholipase B1, membrane-associated (Phospholipase B) (hPLB) (Lysophospholipase) (EC 3.1.1.5) (Phospholipase A2) (EC 3.1.1.4) (Phospholipase B/lipase) (PLB/LIP) (Triacylglycerol lipase) (EC 3.1.1.3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000163803 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q6P1J6 |
| Gene Card | PLB1 |
| Uniprot ID | Q6P1J6 |
| Pfam | PF00657 |
| In ASD | no |
| Allosteric Prediction | yes (0.058548621) |
| Ortholog in Animals | Alpaca_ PLB1 ( ortholog_one2one ) Dog_ PLB1 ( ortholog_one2one ) GuineaPig_ PLB1 ( ortholog_one2one ) Macaque_ PLB1 ( ortholog_one2one ) Mouse_ Plb1 ( ortholog_one2one ) Pig_ PLB1 ( ortholog_one2one ) Rat_ Plb1 ( ortholog_one2one ) Rabbit_ PLB1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | small.intestine |
| Tissue Specificity | Expressed in the epidermis (at protein level). {ECO:0000269|PubMed:12150957}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.025(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6753929 rs11681826 rs10201128 rs7601771 rs34289907 rs2199619 |
| Subcellular location [CC] | Apical cell membrane {ECO:0000250|UniProtKB:O54728}; Single-pass type I membrane protein {ECO:0000255}. Note=Present in the intestinal brush border membranes. {ECO:0000250|UniProtKB:O54728}. |
| Mouse PG classification | NA |
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