| Gene Information | |
|---|---|
| Gene Name | PLB |
| Organism | Homo sapiens (Human) |
| Gene Length | 52 |
| Protein Names | Cardiac phospholamban (PLB) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P26678 |
| Gene Card | PLN |
| Uniprot ID | P26678 |
| Pfam | PF04272 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Heart muscle (at protein level). {ECO:0000269|PubMed:17241641}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1PLP (NMR - ) 1ZLL (NMR - ) 2HYN (NMR - ) 6Y40 (X-ray 1.75A ) |
| DBSNP | rs111033559 rs754782171 rs397516784 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:17241641}; Single-pass membrane protein {ECO:0000255}. Sarcoplasmic reticulum membrane {ECO:0000269|PubMed:12804600, ECO:0000269|PubMed:15598648, ECO:0000269|PubMed:22427649}; Single-pass membrane protein {ECO:0000255}. Mitochondrion membrane {ECO:0000250|UniProtKB:A4IFH6}; Single-pass membrane protein {ECO:0000255}. Membrane {ECO:0000250|UniProtKB:P61014}; Single-pass membrane protein {ECO:0000255}. Note=Colocalizes with HAX1 at the endoplasmic reticulum (PubMed:17241641). Colocalizes with DMPK a the sarcoplasmic reticulum (PubMed:15598648). {ECO:0000269|PubMed:15598648, ECO:0000269|PubMed:17241641}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |