| Gene Information | |
|---|---|
| Gene Name | ATP13A3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1226 |
| Protein Names | Polyamine-transporting ATPase 13A3 (ATPase family homolog up-regulated in senescence cells 1) (Putrescine transporting ATPase) (EC 7.6.2.16) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000133657 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9H7F0 |
| Gene Card | ATP13A3 |
| Uniprot ID | Q9H7F0 |
| Pfam | PF00689; PF00690; PF12409 |
| In ASD | no |
| Allosteric Prediction | no (-0.905029856) |
| Ortholog in Animals | Alpaca_ ATP13A3 ( ortholog_one2one ) Dog_ ATP13A3 ( ortholog_one2one ) GuineaPig_ ATP13A3 ( ortholog_one2one ) Macaque_ ATP13A3 ( ortholog_one2one ) Mouse_ Atp13a3 ( ortholog_one2one ) Pig_ ATP13A3 ( ortholog_one2one ) Rat_ Atp13a3 ( ortholog_one2many ) Rabbit_ ATP13A3 ( ortholog_one2one ) |
| Ohnologs | ATP13A2 |
| Paralogs | ATP2B4, ATP7A, ATP2A3, ATP2B3, ATP1A3, ATP13A2, ATP2B2, ATP13A4, ATP7B, ATP13A5, ATP12A, ATP2B1, ATP1A4, ATP2C2, ATP1A1, ATP1A2, ATP2A1, ATP2A2, ATP4A, ATP2C1, ATP13A1 |
| Tissue | NA |
| Tissue Specificity | Broadly expressed. {ECO:0000269|PubMed:29505581}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Recycling endosome membrane {ECO:0000269|PubMed:29505581}; Multi-pass membrane protein {ECO:0000255}. Early endosome membrane {ECO:0000269|PubMed:29505581}; Multi-pass membrane protein {ECO:0000255}. Late endosome membrane {ECO:0000269|PubMed:29505581}; Multi-pass membrane protein {ECO:0000255}. Note=Mainly targeted to the recycling endosomes and to a lesser extent to the early and late endosomes. {ECO:0000269|PubMed:29505581}. |
| Mouse PG classification | NA |
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