| Gene Information | |
|---|---|
| Gene Name | PRKX |
| Organism | Homo sapiens (Human) |
| Gene Length | 358 |
| Protein Names | cAMP-dependent protein kinase catalytic subunit PRKX (PrKX) (Protein kinase X) (Protein kinase X-linked) (Serine/threonine-protein kinase PRKX) (EC 2.7.11.1) (Protein kinase PKX1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000183943 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P51817 |
| Gene Card | PRKX |
| Uniprot ID | P51817 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | no (-0.2086314) |
| Ortholog in Animals | Alpaca_ PRKY ( ortholog_one2many ) Alpaca_ PRKX ( ortholog_one2many ) Mouse_ Prkx ( ortholog_one2one ) Pig_ PRKX ( ortholog_one2one ) Rat_ Prkx ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PRKG2, PRKACB, PRKACG, PRKG1, PRKACA |
| Tissue | NA |
| Tissue Specificity | Widely expressed (at protein level). Specifically expressed in blood by macrophages and granulocytes according to PubMed:9860982. {ECO:0000269|PubMed:15879576, ECO:0000269|PubMed:16236808, ECO:0000269|PubMed:7633447, ECO:0000269|PubMed:9860982}. |
| Pharmacological Animal Models | 0.026306(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3752362 |
| Subcellular location [CC] | Cytoplasm. Nucleus. Note=cAMP induces nuclear translocation. |
| Mouse PG classification | NA |
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