| Gene Information | |
|---|---|
| Gene Name | PPP1R10 |
| Organism | Homo sapiens (Human) |
| Gene Length | 940 |
| Protein Names | Serine/threonine-protein phosphatase 1 regulatory subunit 10 (MHC class I region proline-rich protein CAT53) (PP1-binding protein of 114 kDa) (Phosphatase 1 nuclear targeting subunit) (Protein FB19) (p99) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000204569 ) 3 ( ENSG00000206489 ) 3 ( ENSG00000227804 ) 3 ( ENSG00000230995 ) 3 ( ENSG00000231737 ) 3 ( ENSG00000235291 ) 3 ( ENSG00000238104 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96QC0 |
| Gene Card | PPP1R10 |
| Uniprot ID | Q96QC0 |
| Pfam | PF08711; PF00642 |
| In ASD | no |
| Allosteric Prediction | no (-0.464151528) |
| Ortholog in Animals | Alpaca_ PPP1R10 ( ortholog_one2one ) Dog_ PPP1R10 ( ortholog_one2one ) GuineaPig_ PPP1R10 ( ortholog_one2one ) Macaque_ PPP1R10 ( ortholog_one2one ) Mouse_ Ppp1r10 ( ortholog_one2one ) Pig_ PPP1R10 ( ortholog_one2one ) Rat_ Ppp1r10 ( ortholog_one2one ) Rabbit_ PPP1R10 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PRR3, ZC3H18 |
| Tissue | NA |
| Tissue Specificity | Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:9450550, ECO:0000269|PubMed:9784381}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.085714(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6ZV2 (NMR - ) |
| DBSNP | rs16897725 |
| Subcellular location [CC] | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00649, ECO:0000269|PubMed:9450550}. Note=Found in discrete nucleoplasmic bodies and within nucleoli. Associates with chromatin during interphase, excluded from condensed chromosomes during early mitosis and is reloaded onto chromosomes at the late telophase (By similarity). {ECO:0000250}. |
| Mouse PG classification | NA |
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