| Gene Information | |
|---|---|
| Gene Name | POU1F1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 291 |
| Protein Names | Pituitary-specific positive transcription factor 1 (PIT-1) (Growth hormone factor 1) (GHF-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000064835 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P28069 |
| Gene Card | POU1F1 |
| Uniprot ID | P28069 |
| Pfam | PF00046; PF00157 |
| In ASD | yes |
| Allosteric Prediction | yes (0.201197783) |
| Ortholog in Animals | Alpaca_ POU1F1 ( ortholog_one2one ) Dog_ POU1F1 ( ortholog_one2one ) GuineaPig_ POU1F1 ( ortholog_one2one ) Macaque_ POU1F1 ( ortholog_one2one ) Mouse_ Pou1f1 ( ortholog_one2one ) Pig_ POU1F1 ( ortholog_one2one ) Rat_ Pou1f1 ( ortholog_one2one ) Rabbit_ POU1F1 ( ortholog_one2one ) |
| Ohnologs | POU2F2, POU2F3, POU3F2, POU3F1 |
| Paralogs | POU2F3, POU4F3, POU3F3, POU6F1, POU4F1, CCDC160, HDX, POU5F1B, POU5F1, POU2F1, POU3F1, POU5F2, POU4F2, POU6F2, POU2F2, POU3F2, POU3F4 |
| Tissue | pituitary.gland |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5WC9 (X-ray 3.15A ) |
| DBSNP | rs1051612 rs35182189 rs104893757 rs104893761 rs104893759 rs104893756 rs104893765 rs1207179169 rs104893766 rs104893758 rs1131815 rs104893764 rs104893762 rs780359925 rs104893755 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:26612202}. |
| Mouse PG classification | LPG |
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