| Gene Information | |
|---|---|
| Gene Name | PKY |
| Organism | Homo sapiens (Human) |
| Gene Length | 1215 |
| Protein Names | Homeodomain-interacting protein kinase 3 (EC 2.7.11.1) (Androgen receptor-interacting nuclear protein kinase) (ANPK) (Fas-interacting serine/threonine-protein kinase) (FIST) (Homolog of protein kinase YAK1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9H422 |
| Gene Card | HIPK3 |
| Uniprot ID | Q9H422 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Overexpressed in multidrug resistant cells. Highly expressed in heart and skeletal muscle, and at lower levels in placenta, pancreas, brain, spleen, prostate, thymus, testis, small intestine, colon and leukocytes. Not found in liver and lung. {ECO:0000269|PubMed:11034606, ECO:0000269|PubMed:9373137, ECO:0000269|PubMed:9725910}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7O7I (X-ray 2.50A ) 7O7J (X-ray 2.81A ) |
| DBSNP | rs34193811 rs34698015 rs35689361 rs266472 rs11032229 rs55807239 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:11034606}. Nucleus {ECO:0000269|PubMed:11034606}. |
| Mouse PG classification | NA |
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