| Gene Information | |
|---|---|
| Gene Name | PKR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 381 |
| Protein Names | cAMP-dependent protein kinase type I-alpha regulatory subunit (Tissue-specific extinguisher 1) (TSE1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P10644 |
| Gene Card | PRKAR1A |
| Uniprot ID | P10644 |
| Pfam | PF00027; PF02197 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.00625(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5KJX (X-ray 1.90A ) 5KJY (X-ray 2.00A ) 5KJZ (X-ray 1.35A ) |
| DBSNP | rs137853303 rs281864786 rs1555814719 rs387906695 rs387906694 rs387906693 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:23115245}. |
| Mouse PG classification | NA |
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