| Gene Information | |
|---|---|
| Gene Name | C9orf2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 380 |
| Protein Names | Tomoregulin-1 (TR-1) (H7365) (Transmembrane protein with EGF-like and one follistatin-like domain) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8IYR6 |
| Gene Card | TMEFF1 |
| Uniprot ID | Q8IYR6 |
| Pfam | PF07648 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed predominantly in brain, and at lower levels in heart, placenta and skeletal muscle. Down-regulated in brain tumors as compared to control brain tissues. {ECO:0000269|PubMed:12743596}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003490(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35624603 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:12743596}; Single-pass type I membrane protein {ECO:0000269|PubMed:12743596}. |
| Mouse PG classification | NA |
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