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Gene Information
Gene Name
PKIA
Organism
Homo sapiens (Human)
Gene Length
76
Protein Names
cAMP-dependent protein kinase inhibitor alpha (PKI-alpha) (cAMP-dependent protein kinase inhibitor, muscle/brain isoform)
Target Name
camp-dependent protein kinase inhibitor alpha
Target Type
NA
Gene Age
544 ( ENSG00000171033 )
Evolutionary Stage
Vertebrata
AlphaFoldDB
P61925
Gene Card
PKIA
Uniprot ID
P61925
Pfam
PF02827
In ASD
no
Allosteric Prediction
no (-0.745620736)
Ortholog in Animals
Alpaca_ PKIA ( ortholog_one2one )
Dog_ PKIA ( ortholog_one2one )
GuineaPig_ PKIA ( ortholog_one2one )
Mouse_ Pkia ( ortholog_one2one )
Pig_ PKIA ( ortholog_one2one )
Rat_ Pkia ( ortholog_one2one )
Rabbit_ PKIA ( ortholog_one2one )
Ohnologs
NA
Paralogs
PKIB, PKIG
Tissue
left.ventricle, pulmonary.valve
Tissue Specificity
NA
Pharmacological Animal Models
NA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB
1CMK
(X-ray
2.90A
)
1JLU
(X-ray
2.25A
)
1Q8T
(X-ray
2.00A
)
1VEB
(X-ray
2.89A
)
1XH4
(X-ray
2.45A
)
1XH5
(X-ray
2.05A
)
1XH6
(X-ray
1.90A
)
1XH7
(X-ray
2.47A
)
1XH8
(X-ray
1.60A
)
1XH9
(X-ray
1.64A
)
1XHA
(X-ray
2.46A
)
1YDR
(X-ray
2.20A
)
2C1A
(X-ray
1.95A
)
2C1B
(X-ray
2.00A
)
2F7E
(X-ray
2.00A
)
2GNI
(X-ray
2.27A
)
2JDS
(X-ray
2.00A
)
2JDT
(X-ray
2.15A
)
2JDV
(X-ray
2.08A
)
2L1L
(NMR
-
)
2UVX
(X-ray
2.00A
)
2UVY
(X-ray
1.95A
)
2UVZ
(X-ray
1.94A
)
2UW0
(X-ray
2.00A
)
2UW3
(X-ray
2.19A
)
2UW4
(X-ray
2.00A
)
2UW5
(X-ray
2.14A
)
2UW6
(X-ray
2.23A
)
2UW7
(X-ray
2.10A
)
2UW8
(X-ray
2.00A
)
2VNW
(X-ray
2.09A
)
2VNY
(X-ray
1.96A
)
2VO0
(X-ray
1.94A
)
2VO3
(X-ray
1.98A
)
2VO6
(X-ray
1.97A
)
2VO7
(X-ray
1.98A
)
3AMA
(X-ray
1.75A
)
3AMB
(X-ray
2.25A
)
3L9L
(X-ray
2.00A
)
3L9M
(X-ray
1.90A
)
3L9N
(X-ray
2.00A
)
3MVJ
(X-ray
2.49A
)
3NX8
(X-ray
2.00A
)
3OOG
(X-ray
2.00A
)
3OVV
(X-ray
1.58A
)
3OWP
(X-ray
1.88A
)
3OXT
(X-ray
2.20A
)
3P0M
(X-ray
2.03A
)
3POO
(X-ray
1.60A
)
3VQH
(X-ray
1.95A
)
3WYG
(X-ray
2.15A
)
3X2U
(X-ray
2.40A
)
3X2V
(X-ray
1.77A
)
3X2W
(X-ray
1.70A
)
4AXA
(X-ray
1.90A
)
4IAC
(X-ray
2.15A
)
4IAD
(X-ray
1.90A
)
4IAF
(X-ray
2.20A
)
4IAI
(X-ray
1.55A
)
4IAK
(X-ray
1.60A
)
4IAY
(X-ray
2.00A
)
4IAZ
(X-ray
1.85A
)
4IB0
(X-ray
1.87A
)
4IB1
(X-ray
1.63A
)
4IB3
(X-ray
2.20A
)
4IE9
(X-ray
1.92A
)
4IJ9
(X-ray
2.55A
)
4O21
(X-ray
1.95A
)
4O22
(X-ray
1.70A
)
4UJ1
(X-ray
1.77A
)
4UJ2
(X-ray
2.02A
)
4UJ9
(X-ray
1.87A
)
4UJA
(X-ray
1.93A
)
4UJB
(X-ray
1.95A
)
4WB5
(X-ray
1.64A
)
4WB6
(X-ray
2.10A
)
4WB7
(X-ray
1.90A
)
4WB8
(X-ray
1.55A
)
4Z83
(X-ray
1.80A
)
4Z84
(X-ray
1.55A
)
5BX6
(X-ray
1.89A
)
5BX7
(X-ray
1.89A
)
5DH9
(X-ray
2.55A
)
5LCP
(X-ray
1.43A
)
5LCQ
(X-ray
1.42A
)
5LCR
(X-ray
1.56A
)
5LCT
(X-ray
1.61A
)
5LCU
(X-ray
1.58A
)
5M0B
(X-ray
1.51A
)
5M0C
(X-ray
1.73A
)
5M0L
(X-ray
1.47A
)
5M0U
(X-ray
1.67A
)
5M6V
(X-ray
1.42A
)
5M6Y
(X-ray
1.37A
)
5M71
(X-ray
1.49A
)
5M75
(X-ray
1.54A
)
5N23
(X-ray
2.09A
)
5XOJ
(X-ray
2.20A
)
6E21
(Other
2.00A
)
6E99
(X-ray
1.88A
)
6E9L
(X-ray
2.80A
)
6FRX
(X-ray
1.88A
)
6QJ7
(X-ray
1.69A
)
6X2U
(X-ray
2.20A
)
6X2V
(X-ray
2.82A
)
6X2W
(X-ray
3.00A
)
DBSNP
NA
Subcellular location [CC]
NA
Mouse PG classification
NA
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