| Gene Information | |
|---|---|
| Gene Name | KRT20 |
| Organism | Homo sapiens (Human) |
| Gene Length | 424 |
| Protein Names | Keratin, type I cytoskeletal 20 (Cytokeratin-20) (CK-20) (Keratin-20) (K20) (Protein IT) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000171431 ) 3 ( ENSG00000263057 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P35900 |
| Gene Card | KRT20 |
| Uniprot ID | P35900 |
| Pfam | PF00038 |
| In ASD | no |
| Allosteric Prediction | no (-0.512320525) |
| Ortholog in Animals | Alpaca_ KRT20 ( ortholog_one2one ) Dog_ KRT20 ( ortholog_one2one ) Macaque_ KRT20 ( ortholog_one2one ) Mouse_ Krt20 ( ortholog_one2one ) Pig_ KRT20 ( ortholog_one2one ) Rat_ Krt20 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | VIM, KRT12, KRT74, INA, NEFM, KRT39, SYNM, KRT13, KRT80, KRT33B, KRT31, KRT77, KRT26, KRT32, KRT73, KRT28, KRT37, KRT38, KRT6B, KRT6A, KRT6C, KRT72, KRT5, KRT222, LMNB1, PRPH, KRT23, KRT4, KRT36, KRT7, KRT34, KRT75, KRT25, KRT76, KRT35, KRT78, KRT24, KRT40, KRT86, KRT83, KRT81, NES, DES, KRT2, KRT9, KRT27, KRT3, KRT84, LMNB2, KRT33A, KRT82, BFSP2, KRT14, KRT16, KRT85, LMNA, KRT8, GFAP, KRT17, KRT79, KRT71, KRT1, KRT19, LMNTD1, NEFL, KRT15, KRT18, KRT10 |
| Tissue | colon, duodenum, small.intestine, small.intestine.Peyers.patch, transverse.colon |
| Tissue Specificity | Expressed predominantly in the intestinal epithelium. Expressed in luminal cells of colonic mucosa. Also expressed in the Merkel cells of keratinized oral mucosa; specifically at the tips of some rete ridges of the gingival mucosa, in the basal layer of the palatal mucosa and in the taste buds of lingual mucosa. {ECO:0000269|PubMed:10973561, ECO:0000269|PubMed:1696264}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs7212483 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:10973561, ECO:0000269|PubMed:1696264}. |
| Mouse PG classification | NA |
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